Windows 11, two mice
(I know the test is in progress, hoping to be helpful)
More than one strange behavior.
Same in switched mode and in multiplexed mode.
1) Sometimes it is not sufficient to move on a window to fully "activate" the mouse on it. In these cases it is necessary a button click. Only after the click all the buttons of the mouse work, in particular the wheel.
2) Mouse 1 active on window 1 and mouse 2 on windows 2.
If I move mouse 1 on window 2 but move mouse 2 out of it , the mouse 1 doesn't work on window 2; I must move back mouse 2 on the window: only then the window reacts also to mouse 1.
3) Sometimes the buttons on the right high angle of a window don't react anymore to the click of both mice. Anyway the window corresponding buttons in the taskbar react regularly.
4) I configured my taskbar to automatically hide.
If I click with mouse 1 on the bar, the bar correctly appears when I move the mouse on and hides when I move the mouse far from it. The bar doesn't react to mouse 2. To let it react to mouse 2, I must click with mouse 2 on the bar: in such a case the behavior "flips over", now the bar doesn't react anymore to mouse 1 passing on it.
Hoping it is clear.